Abstract
Influenza in the 75+ population. Differences in the presentation, risk of hospitalization and complications, exacerbation of chronic diseases, and cognitive disorders
Influenza has been overshadowed by the coronavirus in the recent months, but it is worth taking the time to consider certain aspects of this disease. Vaccination against influenza is highly recommended, especially for the elderly. This patient population most often requires hospitalization and their prognosis is frequently unfavorable. This paper discusses the problem of comorbidities and some differences in the clinical presentation of the infection. The paper also provides an overview of the latest data on reducing the risk of dementia in people vaccinated against influenza.
Piśmiennictwo
1. Zakład Epidemiologii Chorób Zakaźnych i Nadzoru. Pracownia Monitorowania i Analizy Sytuacji Epidemiologicznej. Zachorowania i podejrzenia zachorowań na grypę w Polsce. http://wwwold.pzh.gov.pl/oldpage/epimeld/grypa/index.htm [dostęp: 11.09.2021]
2. https://www.cdc.gov/flu/about/burden/2018-2019.html [dostęp: 11.09.2021]
3. Tenforde MW, Talbot HK, Trabue CH, et al. HAIVEN Investigators. Influenza vaccine effectiveness against hospitalization in the United States, 2019-2020. J Infect Dis 2020;224(5):813-20. doi: 10.1093/infdis/jiaa800
4. Anderson ML, Dobkin C, Gorry D. The Effect of Influenza Vaccination for the Elderly on Hospitalization and Mortality: An Observational Study With a Regression Discontinuity Design. Ann Intern Med 2020;172(7):445-52. doi: 10.7326/M19-3075
5. Smith BJ, Price DJ, Johnson D, et al. Influenza With and Without Fever: Clinical Predictors and Impact on Outcomes in Patients Requiring Hospitalization. Open Forum Infect Dis 2020;7(7):ofaa268. doi: 10.1093/ofid/ofaa268
6. Panhwar MS, Kalra A, Gupta T, et al. Relation of Concomitant Heart Failure to Outcomes in Patients Hospitalized With Influenza. Am J Cardiol 2019;123(9):1478-80. doi: 10.1016/j.amjcard.2019.01.046
7. Šín R, Sedláček D, Hofman S. Symptoms and complications of influenza A in seniors in the 2018-2019 season. Klin Mikrobiol Infekc Lek 2020;26(1):25-9
8. Obata R, Ernst K. Aphasia and confusion – influenza encephalopathy: atypical presentation of influenza. BMJ Case Rep 2020;13(10):e235559. doi: 10.1136/bcr-2020-235559
9. Liu JC, Hsu YP, Kao PF, et al. Influenza Vaccination Reduces Dementia Risk in Chronic Kidney Disease Patients: A Population-Based Cohort Study. Medicine (Baltimore) 2016;95(9):e2868. doi: 10.1097/MD.0000000000002868
10. Luo CS, Chi CC, Fang YA, et al. Influenza vaccination reduces dementia in patients with chronic obstructive pulmonary disease: a nationwide cohort study. J Investig Med 2020;68(4):838-45. doi: 10.1136/jim-2019-001155
11. Wiemken TL, Salas J, Hoft DF, et al. Dementia risk following influenza vaccination in a large veteran cohort running head: Influenza vaccination and dementia. Vaccin 2021: S0264-410X(21)01079-3. doi: 10.1016/j.vaccine.2021.08.046
12. Mastalerz-Migas A, Kuchar E, Nitsch-Osuch A, et al. Recommendations for the prevention, diagnosis and treatment of inFLUenza in adults for Primary care physiciAnS: FLU COMPAS PCP – ADULTS. Family Medicine & Primary Care Review 2020;22(1):81-96
