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Oświadczenie o dostępności danych: Wszystkie dane są dostępne u dr. n. med. Dominika Pruskiego, dominik.pruski@icloud.com
Konflikt interesów: Autorzy nie zgłaszają konfliktu interesów
Artykuł stanowi przedruk i tłumaczenie: Przybylski M, Pruski D, Wszołek K, de Mezer M, Żurawski J, Jach R, Millert-Kalińska S. Prevalence of HPV and assessing type-specific HPV testing in cervical high-grade squamous intraepithelial lesions in Poland. Pathogens 2023;12(2):350. doi: 10.3390/pathogens12020350
ABSTRACT
Prevalence of HPV and assessing type-specific HPV testing in cervical high-grade squamous intraepithelial lesions in Poland
The prevalence and distribution of oncogenic human papillomavirus (HPV) genotypes in women who underwent screening for cervical cancer in the Wielkopolska region, Poland, were assessed, and the correlation of genotypes with the histological results was evaluated. Cervical samples were collected from 2969 women for cervical cancer screening. Participants were screened by liquid-based cytology and HPV genotyping (n = 1654) and referred to colposcopy and punch biopsy (n = 616) if recommended. HPV genotypes 16, 31, 52, 66, 53, and 51 are the most frequent types in the studied population. Genotypes 16 and 31 account for nearly one-fifth of the infections of diagnosed HPV infections. HPV 16, 31, and 52 are found in nearly 80% of premalignant HSIL lesions (CIN 2 and CIN 3). That leads to the conclusion that vaccination programs should cover as many types of HPV as possible and shows the urgent need to vaccinate the Polish population with a 9-valent vaccine.
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