1. TSH pozostaje podstawowym testem w diagnostyce ambulatoryjnej pierwotnej niedoczynności tarczycy.

2. L-tyroksyna jest standardowym sposobem leczenia niedoczynności tarczycy.

3. W przypadku rozpoznania subklinicznej niedoczynności tarczycy decyzja o wdrożeniu leczenia powinna być podejmowana indywidualnie dla każdego chorego.

Piśmiennictwo:

1. Garber JR, Cobin RH, Gharib H, et al. Clinical practice guidelines for hypothyroidism in adults: cosponsored by the American Association of Clinical Endocrinologists and The American Thyroid Asocciation. Endocr Pract 2012;8:1-45.

2. Mechanick JI, Camacho PM, Cobin RH, et al. American Association of Clinical Endocrinologists protocol for standarized production of clinical practice guidelines – 2010 update. Endocr Pract 2010;6:270-83.

3. Vanderpump MP, Tunbrigde WM, French JM, et al. The indidence of thyroid disorders In the community a twenty year follow up of the Wickham Survey. Clin Endocrinol 1995;43: 55-68.

4. Hollowell JG, Staehling NW, Flanders WD, et al. Serum TSH, T4 and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III). J Clin Endocrinol Metab 2012;87:489-99.

5. Negro R, Formoso G, Mangieri T, et al. Levothyroxine treatment In euthyroid pregnant woman with autoimmune thyroid disease: effects on obstetrical complications. J Clin Endocrinol Metab 2006;91:2587-91.

6. Hubalewska-Dydejczyk H, Lewiński A, Milewicz A i wsp. Postępowanie w chorobach tarczycy w ciąży. Endokrynol Pol 2011;62:362-81.

7. Stangaro-Green A, Abalovich M, Alexander E, et al. Guidelines of the American Thyroid Association for the diagnosis and management of thyroid disease during pregnancy and postpartum. Thyroid 2011;21:1081-125.

8. De Groot L, Abalovich M, Alexander EK, et al. Management of thyroid dysfunction during pregnancy and postpartum: an endocrine society clinical practice guideline. J Clin Endocrinol Metab 2012;97:2643-65.

9. Bolk N, Visser TJ, Nijman J, et al. Effects of evening vs morning levothyroxine intake: a randomized double blind crossover trial. Arch Intern Med 2010;170:1996-2003.

10. Wartofsky L, Dickey RA. The evidence for a narrower thyrotropin reference range is compelling. J Clin Endocrinol Metab 2005;90:5483-8.

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