ABSTRACT
A patient with type 1 diabetes and Addison’s disease
Type 1 diabetes is a chronic autoimmune disease which often coexists with other endocrinopathies, including Addison’s disease (0.5-1%). Clinicians should be particularly mindful of adrenal insufficiency symptoms secondary to type 1 diabetes. Patients with Addison’s disease and type 1 diabetes are at high risk of acute life-threatening complications associated with both diseases. Long-term treatment of type 1 diabetes with co-existing primary adrenal insufficiency presents a considerable therapeutic challenge due to the simultaneous insulin and glucocorticoid deficiency. This often requires above-standard management of insulin therapy and hydrocortisone dosing regimen.
KEYWORDS: type 1 diabetes, hypoadrenalism, Addison’s disease.

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